Peter J Ratcliffe Selected Research

dealanylalahopcin

4/2003

Analogues of dealanylalahopcin are inhibitors of human HIF prolyl hydroxylases.

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Peter J Ratcliffe Research Topics

Disease

123	Hypoxia (Hypoxemia) 01/2022 - 01/2002
21	Neoplasms (Cancer) 10/2021 - 05/2002
8	Renal Cell Carcinoma (Grawitz Tumor) 10/2016 - 05/2002
5	Kidney Neoplasms (Kidney Cancer) 10/2016 - 08/2005
5	Anemia 02/2013 - 07/2002
4	Ischemia 01/2021 - 07/2002
4	Inflammation (Inflammations) 09/2017 - 05/2008
3	Iron Deficiencies 01/2016 - 10/2009
3	Carcinogenesis 05/2013 - 04/2007
3	Hereditary leiomyomatosis and renal cell cancer 09/2011 - 04/2007
2	Paraganglioma (Paragangliomas) 10/2021 - 06/2018
2	Polycythemia (Erythrocytosis) 11/2016 - 07/2010
2	Hyperplasia 03/2016 - 01/2016
2	Pulmonary Hypertension 01/2016 - 10/2009
2	Cardiovascular Diseases (Cardiovascular Disease) 06/2015 - 03/2005
2	Cysts 05/2013 - 10/2011
2	Infarction (Infarctions) 08/2012 - 07/2006
2	Hemorrhage 03/2005 - 07/2002
1	Lung Injury 01/2022
1	Acute Lung Injury 01/2022
1	Pheochromocytoma 10/2021
1	COVID-19 01/2021
1	Leukocytosis (Pleocytosis) 01/2019
1	Bone Marrow Failure Disorders 03/2017
1	Hydrocephalus (Hydrocephaly) 10/2016
1	Hypertrophy 01/2016
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 12/2015
1	Chronic Disease (Chronic Diseases) 07/2015
1	Chronic Obstructive Pulmonary Disease (COPD) 07/2015

Drug/Important Bio-Agent (IBA)

62	Oxygen (Dioxygen)IBA 01/2022 - 01/2002
34	Transcription Factors (Transcription Factor)IBA 01/2021 - 07/2002
31	Prolyl Hydroxylases (Prolyl Hydroxylase)IBA 01/2021 - 04/2003
26	Mixed Function Oxygenases (Monooxygenases)IBA 01/2022 - 01/2002
26	EnzymesIBA 10/2019 - 07/2002
18	Proteins (Proteins, Gene)FDA Link 01/2020 - 06/2002
13	DioxygenasesIBA 10/2019 - 06/2003
11	Protein Isoforms (Isoforms)IBA 01/2019 - 09/2004
10	IronIBA 01/2022 - 08/2003
9	Erythropoietin FDA Link 10/2019 - 01/2002
8	Ketoglutaric Acids (Ketoglutaric Acid)IBA 11/2017 - 08/2003
8	OxygenasesIBA 01/2017 - 12/2005
6	Fumarate Hydratase (Fumarase)IBA 05/2013 - 08/2005
4	ChromatinIBA 01/2021 - 06/2011
4	Amino Acids FDA Link 01/2017 - 10/2002
4	AsparagineIBA 03/2011 - 07/2002
4	UbiquitinIBA 05/2007 - 05/2002
3	RNA (Ribonucleic Acid)IBA 01/2020 - 04/2013
3	Biological ProductsIBA 10/2019 - 03/2012
3	Peptides (Polypeptides)IBA 10/2015 - 10/2004
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 02/2012 - 02/2002
3	FumaratesIBA 10/2011 - 08/2005
3	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 06/2002 - 01/2002
2	Prolyl-Hydroxylase InhibitorsIBA 01/2021 - 09/2017
2	Oxidoreductases (Dehydrogenase)IBA 01/2019 - 02/2012
2	Small Interfering RNA (siRNA)IBA 01/2019 - 12/2015
2	Cysteine (L-Cysteine)FDA Link 01/2019 - 10/2011
2	Hemoglobins (Hemoglobin)IBA 11/2016 - 04/2014
2	Intergenic DNA (Junk DNA)IBA 10/2016 - 03/2012
2	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2016 - 02/2012
2	Heme (Haem)IBA 04/2013 - 11/2006
2	Lysine (L-Lysine)FDA Link 05/2011 - 01/2010
2	Histones (Histone)IBA 05/2011 - 01/2010
2	HepcidinsIBA 02/2011 - 02/2009
2	cobaltous chloride (cobalt(II)chloride)IBA 02/2011 - 07/2002
2	DNA (Deoxyribonucleic Acid)IBA 10/2010 - 06/2009
2	4-S-(propionic acid)sulfidocyclophosphamide (PASP)IBA 10/2009 - 12/2008
2	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 12/2008 - 03/2005
2	Messenger RNA (mRNA)IBA 07/2006 - 10/2002
2	Ligases (Synthetase)IBA 10/2004 - 06/2002
1	Interferon Type IIBA 01/2022
1	Macrophage Colony-Stimulating FactorIBA 01/2022
1	Histone MethyltransferasesIBA 01/2021
1	roxadustatIBA 01/2021
1	Facilitative Glucose Transport Proteins (Glucose Transporter)IBA 01/2020
1	Long Noncoding RNAIBA 01/2020
1	PT2385IBA 01/2020
1	Electron Transport Complex IV (Cytochrome c Oxidase)IBA 01/2020
1	beta-apocarotenoid-14',13'-dioxygenase (ADO)IBA 01/2019
1	cysteine sulfinic acidIBA 01/2019
1	Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)IBA 06/2018
1	Ribosomal Proteins (Ribosomal Protein)IBA 03/2017
1	alpha-hydroxyglutarateIBA 10/2016
1	Bromodeoxyuridine (BrdU)IBA 03/2016
1	Serotonin (5 Hydroxytryptamine)IBA 01/2016
1	Dietary Fats (Dietary Fat)IBA 01/2016
1	Uncoupling Protein 3IBA 01/2016
1	A-factor (Streptomyces)IBA 01/2016
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2016
1	Adenosine Triphosphate (ATP)IBA 01/2016
1	AntibodiesIBA 01/2016
1	Chromogranin AIBA 10/2015
1	Pro-Opiomelanocortin (Proopiomelanocortin)IBA 10/2015
1	FMRFamideIBA 10/2015
1	GoldIBA 07/2015
1	Transferrin (beta 2 Transferrin)IBA 07/2015
1	Ferritins (Ferritin)IBA 07/2015
1	Transferrin Receptors (Transferrin Receptor)IBA 07/2015
1	Adrenergic Agents (Adrenergic Drugs)IBA 03/2015

Therapy/Procedure

6	Therapeutics 01/2020 - 10/2003
2	Intravenous Infusions 10/2009 - 12/2008